Fuzz pedals, germ drives, and wah-wahs, especially vintage ones and retro designs, historically had a very low input impedance which naturally rolls off a lot of high end from your guitar. So the loading down effect which is what the Buffer and Buffer+ are designed to counter, actually contributes to the way certain vintage style pedals are meant to sound. So worst case scenario, your vintage style pedal will sound a lot brighter than it otherwise would without the Buffer or Buffer+ in front. Our fuzz and germ pedals have a higher input impedance so there's no audible difference before or after. But as always, experiment and see what works for you!